Placebo Beyond Opinions Center Guest Lecture 2: Human-Centric Molecular Pain Neuroscience
Contact Hours: 1.0
- Average Rating:
- Not yet rated
- Categories:
- Guest Lecture Hybrid Series | Placebo beyond Opinions Center
- Faculty:
- Michele Curatolo, MD, PhD
- Duration:
- 1 Hour
- Course Access:
- Expires 30 day(s) after program date.
Description
Thank you for registering for the Guest Lecture, Human-Centric Molecular PainNeuroscience with Dr. Michele Curalto. Dr. Curatolo studies gene expression to understand the nature of pain. His lecture will address how the mechanism of pain can inform personalized pain management.
Important: This event will take place in person at UMSON in Room 211. If you are able, please plan to attend in person.
For those who cannot attend onsite, the live broadcast will be available here on CE21.
Please remember to complete the evaluation once the session is finished.
The discovery of targets for pain therapeutics has mostly relied on animal studies. However, there are species differences in nociceptive mechanisms. Human pain is influenced by various environmental factors and manifests in multiple ways, leading to substantial phenotypic heterogeneity. The availability of tissues collected from patients with chronic pain offers a promising opportunity to study the molecular mechanisms of human pain in the context of its multidimensionality. Initial data from studies that applied transcriptomics to dorsal root ganglia from patients with neck pain and intervertebral disc tissue from patients with low back pain have revealed the expression of genes potentially relevant to human nociception. This research has the potential to shed light on which transcriptional changes are relevant to specific pain phenotypes and pave the way for the development of more effective, individualized therapeutics.
Learning objectives:
After attending this lecture, participants will be able to:
1) Appreciate the opportunities and challenges of studying the molecular mechanisms of pain in patients
2) Learn about transcriptional changes in the dorsal root ganglion that can drive human chronic neck pain
3) Learn how transcriptomics of degenerated discs can advance the knowledge of human chronic low back pain
Nursing Continuing Professional Development
Nurses may receive 1.0 contact hour for participating and completing the evaluation of this educational activity. Partial credit is not provided. Participants receive a certificate via email from UMSON Office of Professional Education approximately two to four weeks after submitting their completed evaluation form. All requests must be received within 30 days of the event. The University of Maryland School of Nursing is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.
Faculty
Michele Curatolo, MD, PhD Related Seminars and Products
University of Washington, Department of Anesthesiology and Pain Medicine
Dr. Michele Curatolo is professor of Anesthesiology and Pain Medicine at the University of Washington, endowed professor for medical education, and research and director of the interventional pain program. His expertise is in pain management, education and research.
After receiving his M.D. at the University of Messina in Italy, he completed his Ph.D. at the University of Aalborg in Denmark. Clinical leadership roles include a 16-years activity as chief of the Division of Pain Therapy in the Department of Anesthesiology and Pain Therapy at the University of Bern, Switzerland, where he was interim chair of the department.
Having published over 220 publications, his research focuses on studying nociceptive processes in humans to improve the understanding of pain and facilitate the development of treatments. Dr. Curatolo was one of the initiators of the field of ultrasound-guided interventional pain procedures. His research has been supported in Switzerland by the Swiss Science National Foundation, the Swiss Federal Funding Agency, and currently, in the USA, by several grants from the National Institute of Health. He has been awarded several prizes for his scientific work, as well as an honorary doctorate at the University of Aalborg, Denmark, and a honorary membership of the Swiss Pain Society.
With an extensive experience in university teaching and mentoring, he has been invited to hold over 300 lectures, courses and workshops in national and international meetings. He have served as reviewer for multiple high ranked scientific journals, funding agencies and external academic institutions. Current journal editorial responsibilities include membership in the editorial board of Pain, and role as section editor of the European Journal of Pain and the Scandinavian Journal of Pain.